Menofort
MENOFORT CAPSULES Soy isoflavones, found naturally, are phytoestrogens—plant-based compounds that mimic estrogen in the body. They have been studied for various health benefits, particularly for women.
1. Menopausal Symptom Relief
Hot Flashes and Night Sweats: MENOFORT Soy isoflavones, particularly genistein, may reduce the frequency and severity of hot flashes in some menopausal women. Studies suggest a daily dose of 50–100 mg Some trials show in gut microbiota, which affect isoflavone metabolism (e.g., equol production, which enhances estrogenic effects in 30–50% of people, higher in Asian populations).
2. Cardiovascular Health
MENOFORT Soy isoflavones, can lower total and LDL cholesterol by 2–3% and raise HDL cholesterol by about 3%. These effects are more pronounced when replacing animal proteins high in saturated fat.
Blood Pressure: Some studies show isoflavones reduce systolic blood pressure in early menopause and diastolic blood pressure (by 3–8% in some cases), especially in those with slightly elevated levels.
Vascular Function: Isoflavones may improve endothelial function and slow subclinical atherosclerosis, potentially reducing heart disease risk, particularly in postmenopausal women.
Epidemiological Evidence: In Asian populations with high soy intake (15–60 mg/day isoflavones), heart disease rates are lower, though other dietary and lifestyle factors may contribute.
3. Bone Health
MENOFORT Soy isoflavones help slow bone loss in postmenopausal women, who are at higher risk for osteoporosis due to declining estrogen. Some studies show improved bone turnover markers or increases in bone mineral density (BMD) with doses of 40–110 mg/day. Effects more stronger in perimenopausal or early postmenopausal women.
4. Cancer Risk Reduction
Breast Cancer: Observational studies, particularly in Asian populations, suggest that high MENOFORT soy isoflavone intake (e.g., 25–50 mg/day) is linked to a 21–32% lower risk of breast cancer, In breast cancer survivors, higher soy intake was associated with a 25–60% reduction in recurrence, particularly for estrogen-negative tumors or those not using tamoxifen. However, concerns persist about isoflavones’ estrogen-like effects in high-risk women, though human studies show no increased risk or worsening of prognosis.
Other Cancers: soy isoflavones reduce the risk of endometrial, ovarian, prostate, and lung cancers, possibly due to their antioxidant and anti-estrogenic propertie
Mechanism: Isoflavones bind preferentially to estrogen receptor beta, which may inhibit cancer cell growth, unlike estrogen’s binding to alpha receptors, which can promote it.
5. Cognitive Function
Some studies suggest MENOFORT soy isoflavones (50–100 mg/day) improve cognitive function, particularly visual memory, in people under 60, with stronger effects in non-US populations. A 2020 meta-analysis found benefits for overall cognition and memory Isoflavones interact with estrogen receptor beta in brain regions linked to executive function and memory and exhibit antioxidant and anti-inflammatory properties that protect against dementia.
6. Other Potential Benefits
Anti-Inflammatory and Antioxidant Effects: MENOFORT Isoflavones have impressive anti-inflammatory properties in animal models and some human studies, potentially reducing the risk of chronic diseases like heart disease, diabetes, and cancer.
Type 2 Diabetes: Observational data from the Nurses’ Health Study suggests higher isoflavone intake is linked to a lower risk of developing type 2 diabetes
Menstrual Health: Isoflavones reduce menstrual irregularity and cyclic mastalgia (breast pain) in non-menopausal women.
MENOFORT Soy isoflavones offer potential benefits for menopausal symptom relief, cardiovascular health, bone health, cognitive function, and cancer risk reduction.
